The Russell 2000 small cap index has underperformed the larger caps materially over the last two years. It may come as a surprise, but small cap stocks made their all-time high in September 2018.

Biotech is arguably the most exciting sector to invest in. This year, the NYSE Arca Biotechnology Index has more than doubled the S&P 500’s 14.6% total return with a 32.5% gain.