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My name is Larry Smith. I spent the first 25 years of my career working on Wall Street as an analyst with a primary focus on biotechnology and pharmaceutical stocks. However, I have also covered companies in several other industries. Most of this time was spent with Smith Barney and Hambrecht ...more

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Update On Currently Recommended Stocks
In this report I update my objectives and include several buy recommendations in the biotech sphere.
Northwest Biotherapeutics: Thoughts On Why The Phase 3 Trial Of DCVax-L Is Ongoing
The phase 3 trial of DCVax-L in newly diagnosed glioblastoma is continuing even though it has passed the 248 PFS events (mPFS is a primary endpoint) and has probably surpassed 233 OS events (mOS is an independent co-primary endpoint).
Northwest Biotherapeutics, Bristol-Myers Squibb: Success For The Yervoy-Opdivo Combination
The stoppage at an interim analysis of Bristol-Myers Squibb’s’ Checkmate-214 trial provides meaningful information into assessing the potential for success of Northwest Biotherapeutics.
Portola: Potential Launch Date For Bevyxxa And Price Announcement
Portola ended 2Q, 2017 with $270 million of cash which management states can fund operations into 1Q, 2018. The Company is going to require a very significant amount of cash to fund the launch of Bevyxxa and AndexXa.
Northwest Biotehrpeutics: How Does DCVax-L Clinical Data Compare To The CAR-T Therapy Axi-Cel?
It is a paradox that people can look at the Kite phase 2 data on Axi-Cel and pronounce it as stunning as does Biotech Hawk and in the next breath dismiss phase 1/2 data on DCVax-L that appears much more encouraging.
Alimera Sciences: Company Achieves Breakeven Pretax Cash Flow In 2Q, 2017 Despite Slow Unit Demand For Iluvien
Alimera has made dramatic improvements in its cash flow situation and has done a very respectable job in building sales. Alimera is not far away from being a cash generating, profitable pharmaceutical company.
Cryoport: As Its Clients Transition From Clinical Development To Commercial, Growth Could Be Explosive
Cryoport is in the very early stages of corporate development and has only minimal sales ($9.8 million on a trailing twelve months basis). It is still too small to catch the eyes of large investors.
Portola Pharmaceuticals: AndexXa BLA Resubmitted; Reiterating Buy
Portola issued a press release on August 3, 2017, that reported it had just resubmitted the BLA for AndexXa, which is in line with prior management guidance.
Cytokinetics: Reiteration Of My Long Standing Buy Recommendation Based On An Extraordinary Pipeline
CYTK reported a loss of $29 million in the second quarter and currently has a $332 million cash position which management indicates can carry the Company through 2H, 2019.
Cryoport: Upping 2020 Price Target From $14.50 To $20.00 (CYRX, Buy, $6.89)
Cryoport announced today that it had been selected by Novartis to provide logistics for NVS’ lead CAR-T product tisagenlecleucel (also known as CTL-019) upon approval.
Northwest Biotherapeutics: Why The Phase 3 Trial Of DCVax-L In Newly Diagnosed Glioblastoma Patients Has A Good Chance For Success
This report is an extensive update on almost everything I know about the DCVax-L phase 3 trial and is over 20 pages long. The catalyst for this report was the recent information on the still blinded phase 3 trial presented in June at ASCO.
Antares: Pipeline Is Bursting With Late Stage Products (ATRS, $2.77, Buy)
Antares has an impressive portfolio of seven new products that could lead to explosive growth over the next four years.
1 to 12 of 12 Posts