Visualizing The World’s Biggest Pharmaceutical Companies

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Bubble map of the largest pharmaceutical companies in the world

Who are the World’s Biggest Pharmaceutical Companies?

Some of the world’s biggest pharmaceutical companies have played a central role in the COVID-19 pandemic.

However, it’s likely no surprise that the pandemic has also been great for many healthcare businesses. In fact, in 2020 alone, the world’s 50 largest pharmaceutical companies still combined for a whopping $851 billion in revenues.

In this graphic, using data from Companies Market Cap, we list the largest pharmaceutical companies in the world by market capitalization. It’s worth noting this list also includes healthcare companies that work closely with pharmaceuticals, including biotech, pharmaceutical retailers, clinical laboratories, etc.

The Pharmaceutical Leaders

To start, here are the top five biggest pharmaceutical companies in the world at the moment by market capitalization:

1. Johnson & Johnson

The pharmaceutical and consumer goods giant is worth $428.7 billion in market cap. They developed the third vaccine authorized for use in the U.S. and were named among the TIME100 Most Influential Companies List in 2021.

2. Roche

The Swiss pharmaceutical giant is at the forefront of oncology, immunology, infectious diseases, ophthalmology, and neuroscience. In 2019, Roche’s pharma segment sales rose by a healthy 16% to $53 billion.

3. Pfizer

Despite being the leading COVID-19 vaccine manufacturer in North America, Pfizer slid in the rankings to third place. The company has recently gained momentum, especially in the past quarter, with Q2’2021 revenues of $19.0 billion, reflecting a 86% operational growth from 2020.

4. Eli Lilly

Eli Lilly has taken a significant step towards establishing itself as a pharmaceutical industry leader. Having a market cap value of $125 billion in 2019, Eli Lilly has jumped to a current value of $214.9 billion, a significant growth of 72%.

5. Novartis

The second-biggest pharmaceutical company out of Switzerland, Novartis has been the face of the pharma industry for about 25 years. The primary manufacturer for the most recognizable drugs on the market pulled in a revenue of over $48 billion in 2020, a 3% increase compared to 2019.

Here’s how all the biggest pharmaceutical companies in the world stack up against each other:


Rank Company Name Market Cap Value Country      
1 Johnson & Johnson
$428.66 B 🇺🇸 USA      
2 Roche
$320.41 B 🇨🇭 Switzerland      
3 Pfizer
$219.39 B 🇺🇸 USA      
4 Eli Lilly
$208.99 B 🇺🇸 USA      
5 Novartis
$207.70 B 🇨🇭 Switzerland      
6 Merck
$191.67 B 🇺🇸 USA      
7 Novo Nordisk
$187.83 B 🇩🇰 Denmark      
8 Astrazeneca
$152.28 B 🇬🇧 UK      
9 Bristol-Myers Squibb
$145.80 B 🇺🇸 USA      
10 Amgen
$136.50 B 🇺🇸 USA      
Rank Company Name Market Cap Value Country      
11 Sanofi
$130.37 B 🇫🇷 France      
12 CVS Health
$110.49 B 🇺🇸 USA      
13 Gilead Sciences
$83.62 B 🇺🇸 USA      
14 Moderna
$83.25 B 🇺🇸 USA      
15 Merck KGaA
$80.61 B 🇩🇪 Germany      
16 Bayer
$59.43 B 🇩🇪 Germany      
17 Jiangsu Hengrui Medicine
$58.51 B 🇨🇳 China      
18 Regeneron Pharmaceuticals
$55.83 B 🇺🇸 USA      
19 Biogen
$55.00 B 🇺🇸 USA      
20 BioNTech
$54.23 B 🇩🇪 Germany
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William K. 1 month ago Member's comment

Interesting for certain. The biggest appearto have the most resources for research, but they are not always the champions for discovery.

And it appears that there is still room for growth. So we will continue to have winners and losers.