Image Source: Grok
 

Introduction

Evolve® Rodent Birth Control™, made by SenesTech, is designed to stop the rapid reproduction of rats - just two rats in one year can become 15,000 - without the collateral damage to dogs, coyotes, foxes and birds of prey that comes with using rodenticides. This article provides some insight into the rat birth control concept.

About SenesTech Inc.

SenesTech Inc. (SNES) is a micro‑cap (just $12.2M) biotech company with birth‑control products for rats and mice. Its products - soft bait, in sausage form -attract rodents without harming the rodents, people or pets in the process.

How Bad is the Rat/Mouse Problem In the U.S.?

Data says 11.6% of all U.S. homes show signs of rodent infestation — that’s more than 1 in 10 households. Chicago remains the most rat‑infested city in the U.S. (10 years running) while East Coast cities like New York, Philadelphia, Washington D.C., Baltimore, and Pittsburgh are major hotspots and, interestingly, Los Angeles recently overtook Chicago in some rankings, showing the problem is spreading westward.

What Is the Total Addressable Market Size Of Rat/Mouse Control Products America?

According to Statista, the total addressable market (TAM)  size of rat/mouse control products (including traps, rodenticides, birth-control bait/stations and devices) currently is estimated to range from $1.5B to $2.5B and will grow to somewhere between $2.5B and $4.0B by 2030.

Is SenesTech's Product Safe? How Does It Work?

Evolve - made from non-hazardous ingredients like cottonseed oil - which decreases sperm production and ovarian follicle growth in rats and mice - is a soft bait that has been exempted by the Environmental Protection Agency (EPA) from the requirement that it be registered by the Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) Section 25(b) since it poses little or no risk to people or the environment, including non-target animals.

Who Are SenesTech's Competitors?

SenesTech has no true “direct” competitors in the fertility‑control niche.

Strategic Positioning

The markets for SenesTech products are municipalities, retailers, pest management professionals, the e-commerce sector and the international marketplace.

1. Municipalities: 
   • The rodent situation in the U.S. is significant, widespread, and getting worse, particularly in cold‑weather regions as winter dramatically increases infestations as rats and mice move indoors for warmth and food. Of the approximately 19,000 municipalities in the U.S. (specifically cities, towns, villages, boroughs) 4,200 are in cold-weather states.
   • In a June 25, 2025 press release, SenesTech detailed a successful field trial conducted with the Irvine Campus Housing Authority at UC Irvine which showed that the rat population declined to the extent that  rodenticides were fully eliminated from all  bait stations deployed across common areas, demonstrating practical efficacy.
   • California has significantly restricted rodenticides, banning most uses under recent legislation to protect wildlife, with only limited exemptions for agriculture and public health emergencies and this regulatory shift puts products like Evolve in a favorable position as consumers and municipalities seek compliant, non-lethal options.
   • Municipal revenue grew 139% year-over-year due to expanded deployments in New York City, Chicago, and other locations, reflecting increased adoption in diverse urban settings. Current programs continue to focus on controlled deployments in high-impact areas, laying the groundwork for potential large-scale expansion. 
2. Retailers: Retail revenue grew 254% year-over-year, driven by expanded adoption by Ace Hardware, and follow-on orders from Bradley Caldwell, a wholesaler serving over 8,000 retail locations in the Northeast.
3. Pest management professionals: Pest management professionals boosted company revenue by 29% year-over-year and 72% sequentially, and now represents nearly 20% of the Company's overall Q3 2025 revenue,
4. e-commerce sector: Evolve became available across several major online retail platforms during the year, including Tractor Supply Co., (TSCO) Home Depot (HD), Lowe’s (LOW), Amazon (AMZN), Walmart (WMT), and Ace Hardware, which materially broadened consumer access to the product. in total, the revenue of the e-commerce sector accounted for 54% of quarterly revenue
5. International market: Evolve has entered the international market with shipments to Hong Kong, the Netherlands, Belize and the Maldives, with plans for Australia and New Zealand.

Why Is SenesTech Being Sued By Liphatech?

Liphatech, a major rodenticide manufacturer, sued SenesTech for a breach‑of‑contract under 28 U.S.C. §1332 Diversity – Breach of Contract in December, 2024, alleging that SenesTech violated terms of an agreement between the two companies, the specific details of which are currently unknown.

Editors' note: The Company believes the case is without merit and is actively defending the case.

SenesTech Financials

SenesTech has reported consistent revenue growth during the past 3 quarters going up 9.5% in Q3, 2025, to $690K, representing a 44% increase YoY, driven almost entirely by its EVOLVE rodent birth‑control line which accounted for 79% of sales in Q1 and 85% in Q3. Gross Profit went up 39% during the same period thanks to a healthy Gross Margin of 63% although its adjusted EBITDA loss, which closely tracks their cash utilization, was $1.32  million which is the best in the company's history. According to management, the balance sheet cash position of $10.2M has the ability to allow the company to reach profitability without proactively raising any additional dilutive capital but doesn’t solve the path to profitability.

SenesTech Stock Performance

SNES stock has declined 65.6% in the past 6 months but has only gone DOWN 13.8% in the past month.

Conclusion

While SNES is a potentially awesome long‑term investment given its lack of competition, it is highly speculative as its market cap remains very small, which typically implies high volatility and elevated dilution risk, and its low liquidity, sparse analyst coverage and long history of price decline. The key variables of its on-going success depend on management's execution of its marketing plan, the adoption of its unique concept by the sectors constituents and its access to capital. Of late, they have been doing an admirable job.

Related Articles:
SenesTech's 43% Revenue Surge That Nobody's Talking About
SenesTech Remains Undervalued With Increasing Revenues And Global Product Distribution
SenesTech's Big Play On Small Pests
SenesTech Has Built A Better Mouse Trap

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