Biotech Alert: Searches Spiking For These Stocks Today - Friday, June 2

TM Editors' note: This article discusses a penny stock and/or microcap. Such stocks are easily manipulated; do your own careful due diligence.

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These names in the biotech sector are seeing a substantial increase in search activity today, as determined by InvestingChannel. They include: 

  • Akebia Therapeutics (AKBA), with a 140% surge in interest.
  • Corvus Pharmaceuticals (CRVS), with a 132% surge in interest.
  • Mirati Therapeutics (MRTX), with a 112% surge in interest.
  • Iovance Biotherapeutics (IOVA), with a 110% surge in interest.
  • Coherus BioSciences (CHRS), with a 90% surge in interest.

Pipeline and Key Clinical Candidates

Akebia Therapeutics is a fully integrated biopharmaceutical company that says its purpose is "to better the lives of people impacted by kidney disease."

Corvus Pharmaceuticals is a clinical-stage biopharmaceutical company that says it is "pioneering the development of ITK inhibition as a new approach to immunotherapy for a broad range of cancer and immune diseases."

The company's lead product candidate is CPI-818, an investigational, oral, small molecule drug that selectively inhibits ITK and is in a mid-stage clinical trial for patients with T cell lymphoma. Its other clinical-stage candidates are being developed for a variety of cancer indications.

Mirati Therapeutics is focused on bringing forward therapies that address areas of high unmet medical need, including lung cancer, and advancing a pipeline of novel therapeutics targeting the genetic and immunological drivers of cancer.

Iovance Biotherapeutics is focused on developing and delivering tumor infiltrating lymphocyte, or TIL, therapies for patients with cancer. Its lead late-stage TIL product candidate, lifileucel for metastatic melanoma, "has the potential to become the first approved one-time cell therapy for a solid tumor cancer," said the company, adding that its TIL platform has "demonstrated promising clinical data across multiple solid tumors."

Coherus is a commercial-stage biopharmaceutical company focused on the "research, development, and commercialization of innovative immunotherapies to treat cancer and the commercialization of our portfolio of FDA-approved therapeutics." Coherus’ strategy is to build a leading immuno-oncology franchise funded with cash generated through net sales of its diversified portfolio of FDA-approved therapeutics.

Here is a brief rundown of recent news in regards to these highly-searched stocks.

June 2

In a regulatory filing, Akebia Therapeutics disclosed that on May 30, Keryx Biopharmaceuticals, a wholly owned subsidiary of Akebia, and Panion & BF Biotech entered into a settlement and license agreement with Zydus.

This settlement resolves patent litigation brought by Keryx and Panion in response to Zydus' Paragraph IV certification notice letter regarding their Abbreviated New Drug Application, or "ANDA," seeking approval to market a generic version of Auryxia tablets prior to the expiration of the applicable patents.

Coherus Biosciences announced that it plans to launch its Humira biosimilar, Yusimry, with a list price of $995 per carton, which is the lowest price announced to date of any Humira biosimilar in the United States, H.C. Wainwright wrote in a research note. The analyst said the "steep discount" shows Coherus is prepared to be low-cost provider in the market for Humira biosimilars.

With Humira currently priced at $6,922 per carton of two autoinjectors, Coherus' represents about an 85% discount from the originator, said H.C. Wainwright. It notes that by discounting so steeply, Yusimry is going to avoid the specialty tier and therefore avoid the 20%-30% copays that accompany those drugs.

"By coming to market at such a steep discount, we expect Coherus is going to get the attention of payers," wrote Wainwright. The firm's market intelligence suggests that Abbvie's contracting strategy will not exclude Coherus as long as Humira is at parity and not disadvantaged through a prior authorization.

May 31

Piper Sandler upgraded Akebia to Overweight from Neutral with a price target of $4, up from $2, after the company received a response from the FDA on a path forward for vadadustat.

The stock's risk/reward skews positive after the FDA outlined information to be included in a new drug application resubmission, which did not include the generation of additional clinical data, the analyst told investors in a research note. Given the news, the firm is layering the U.S. vadadustat opportunity back into its model with end-user revenue approaching $375 million by fiscal year 2028.

May 30

Ladenburg raised the firm's price target on Corvus Pharmaceuticals to $10 from $4 and keeps a Buy rating on the shares. The analyst believes CPI-818's demonstrated efficacy so far will not be limited to T-cell lymphoma only, but will likely be applicable further in a number of solid tumors.

May 26

Iovance Biotherapeutics announced that the U.S. Food and Drug Administration accepted its Biologics License Application for lifileucel for patients with advanced melanoma. The FDA granted lifileucel Priority Review and assigned Nov. 25, 2023 as the target action date for a decision under the Prescription Drug User Fee Act.

The FDA is not currently planning to hold an advisory committee meeting to discuss this application and, after a preliminary review, has not at this time identified any potential review issues. Lifileucel is a TIL therapy intended for patients with advanced melanoma who progressed on or after prior anti-PD-1/L1 therapy and targeted therapy, where applicable. There are no FDA approved therapies in this treatment setting.

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George Lipton 3 months ago Member's comment

It’s getting more and more exciting, I thought Friday would start the running. I agree this is going to start sometime next week all the way up to Lugano. After Lugano then we can expect some type of partnership (is my guess & Miller said “we need a partner”). They must have already been having discussions I would bet! 😂 I guess we are betting!

I keep calculating $10-20-30+. I see it happening, it’s gonna happen!

George Lipton 3 months ago Member's comment

This guy bought 50k July $4 calls around.40 ($20k) on top of his stock position, I even verified the volume when he said.

George Lipton 3 months ago Member's comment

Actually $22,500 by mid July he need the stock at $4.45 by mid July to breakeven, that’s bullish, I think it goes higher by then

Andrew Armstrong 3 months ago Member's comment

$CHRS $MRTX $AKBA $CRVS $IOVA Crvs should be running starting Monday One on one meeting with Richard Miller and Jeffries Co on June 7 Then Lugano on June 17th.

Mad About Money 3 months ago Member's comment

Lugano data isn't on the 17th, it's actually a few days before. From the press release: 
"The poster will be available to attendees in the poster hall on Wednesday, June 14 from 12:00 – 6:00 pm CEST and Thursday-Friday, June 15-16 from 10:00 am – 6:00 pm CEST. It will also be accessible to attendees beginning on Wednesday, June 14 at 8:30 am CEST in the e-poster gallery." 
And looks like they'll have it released on their website in the morning on the 15th.

Danny Straus 3 months ago Member's comment