The global cold plasma market was valued at USD 167.8 million in 2025 and is expected to reach USD 495.9 million by 2033, expanding at a 14.6% CAGR from 2026 to 2033. The market is projected to increase from USD 191.1 million in 2026 to USD 495.9 million by 2033.
North America led the global cold plasma market in 2025, accounting for 40.4% of total revenue. Market expansion is being supported by developments across the healthcare sector and growing demand for advanced technologies that can improve treatment procedures while supporting safer and less invasive patient care.
Cold Plasma Market at a Glance
2025 market size: USD 167.8 million
2026 estimated market size: USD 191.1 million
2033 projected market size: USD 495.9 million
CAGR, 2026–2033: 14.6%
Leading region: North America
North America revenue share, 2025: 40.4%
Source: Grand View Research, IR Documents, Primary Interviews, Paid Databases
What Is Driving the Cold Plasma Market?
Cold plasma, also referred to as non-equilibrium plasma, is a partially ionized gas in which the temperatures of its constituents differ significantly. It is produced by supplying energy to gases, generating reactive species that can be used in applications such as medical treatments, sterilization, and food safety.
Unlike high-temperature plasma technologies, cold plasma can support these applications without the harmful effects associated with high-temperature plasmas. This characteristic is increasing interest in cold plasma as a technology for applications that require effective processing while limiting thermal impact.
The technology is gaining traction across healthcare, food safety, textiles, and other industries. Its expanding use in wound healing, sterilization, cancer treatment, food decontamination, and other applications is contributing to market growth.
Download a free sample report or claim your copy of this full market intelligence report
Key Market Trends & Insights
Atmospheric Pressure Plasma Leads by Pressure
The atmospheric pressure cold plasma segment accounted for 63.8% of the global market in 2025, making it the leading segment by pressure. The growing adoption of atmospheric cold plasma is supported by its potential to provide processing and treatment solutions without relying on harmful chemicals.
Wound Healing Remains a Leading Application
Wound healing held the largest application share in 2025. The growing use of cold plasma technologies in medical treatment is contributing to demand, particularly as healthcare providers seek advanced approaches that can support patient care while reducing the invasiveness of treatment procedures.
Sterilization and Infection Control Create New Opportunities
Cold plasma's antimicrobial properties are increasing its relevance in sterilization and infection-control applications. Healthcare facilities are seeking effective technologies to address infection risks, while other industries are exploring cold plasma for decontamination and sustainable processing.
Looking for more in-depth data focusing on specific segments or regions? Get this report customized with inclusion of custom data sets to suit your exact business needs.
Cold Plasma and Hospital-Acquired Infections
The increasing incidence of hospital-acquired infections (HAIs) represents an important growth factor for the cold plasma market. Healthcare facilities are looking for effective sterilization and infection-control technologies that can help improve patient safety.
According to the World Health Organization (WHO), HAIs affect hundreds of millions of patients worldwide each year and can contribute to increased morbidity, longer hospital stays, and higher healthcare costs. In the U.S., the Centers for Disease Control and Prevention (CDC) estimates that approximately 1 in 31 hospital patients has at least one HAI on any given day, contributing to about 99,000 deaths annually.
The WHO's Global Report on Infection Prevention and Control (2024) further highlights the scale of the issue. Among patients in acute-care hospitals, approximately 7 out of every 100 patients in high-income countries and 15 out of every 100 patients in low-income countries acquired at least one HAI during their hospital stay.
These infection-control challenges are strengthening interest in cold plasma because of its antimicrobial capabilities and potential applications in sterilization and healthcare environments.
Cold Plasma Applications Expand Across Industries
Beyond healthcare, cold plasma technology is being adopted across industries such as textiles and food safety. Increasing demand for sustainable and efficient processing technologies is creating additional opportunities for market expansion.
In food-related applications, innovations in decontamination are supporting interest in cold plasma-based approaches. In medical applications, technological advances are expanding its potential in areas such as wound treatment, sterilization, and cancer treatment.
Advancements in atmospheric cold plasma technology are also supporting adoption by offering processing approaches that can reduce dependence on harmful chemicals. This combination of sustainability, efficiency, and application flexibility is increasing the technology's attractiveness across multiple industries.
Cold Plasma and Airborne Virus Removal
Research from the University of Michigan has identified cold plasma as an effective approach for removing dangerous airborne viruses. According to the supplied research reference, non-thermal plasma can remove up to 99% of viruses in fractions of a second.
Such findings create potential opportunities for cold plasma technologies in applications involving airborne pathogens and respiratory health. The ability to rapidly reduce viral presence could support further research and development of cold plasma solutions for healthcare environments and related applications.
Regional Highlights
North America was the leading regional market in 2025, with a 40.4% revenue share. The region's position is supported by developments in healthcare and demand for advanced treatment, sterilization, and infection-control technologies.
The U.S. cold plasma industry is a major contributor to the global market. Increasing attention to patient safety, infection control, and advanced medical technologies is supporting the adoption and development of cold plasma solutions in the country.
Market Size & Forecast
Year | Market Size |
2025 | USD 167.8 million |
2026 | USD 191.1 million |
2033 | USD 495.9 million |
CAGR, 2026–2033 | 14.6% |
The market's projected expansion from USD 191.1 million in 2026 to USD 495.9 million by 2033 reflects increasing adoption across healthcare and industrial applications. Demand for non-invasive treatment technologies, antimicrobial solutions, sustainable processing, and advanced decontamination methods is expected to remain central to market development.
Key Cold Plasma Companies
The companies profiled in the cold plasma market study include:
Apyx Medical
neoplas med GmbH
Adtec Healthcare Limited
terraplasma GmbH
CINOGY System GmbH
Explore our dedicated business services:
S. Healthcare Facility Mapping & Intelligence Portal – Claims analytics (MS-DRG, service lines, ICD-10 outpatient, APC reimbursement, CPT-level) plus hospital-level financials (balance sheet, income statement, uncompensated care, financial health dashboards), covering 25,000+ healthcare facilities — including 7,000+ hospitals, independent pharmacies, freestanding EDs, concierge physicians, and ASCs.
Brainshare Consulting – End-to-end business consulting services including Opportunity assessment, GTM support, Competitive intelligence, and Consumer Analytics.
Custom Research – Get a market intelligence report tailored to your specific requirements and aligned with your business goals.
Consumer Insights – Capture real, evolving consumer sentiment and behavior to help you make data driven strategies.
Horizon Databooks – Access the world’s largest portal of Market Reports & Statistics
Investment Insights – Make investment decisions with data driven insights, powered by domain and technology
Signal (Pricing Intelligence) - Commodity price intelligence to drives strategic advantage.
About us:Grand View Research, a market research and consulting company, provides syndicated research reports, customized research reports, and consulting services. Grand View Research database is used by the world's renowned academic institutions and Fortune 500 companies to understand the global and regional business environment. Our database features thousands of statistics and in-depth analysis on 46 industries in 25 major countries worldwide.
Comments
Log in or sign up to join the conversation.