However, I do question the 90%+ efficacy claims, merely because participants in trials were not necessarily exposed to COVID at all, unless they inadvertently came across the situation. It might be presumed intelligent volunteers were of course not the no-mask/hoax crowd, and therefore were responsible, careful, and hence less like to be exposed. Now there have been earlier very effective vaccines, measles and the Salk Polio vaccine come to mind. Or the newer as well as synthetic Shingles vaccine, but those actually are exceptions.
Those of course weren't messing with human DNA, in the manner these new ones do, so that probably underlies speculative residual concern, that is being dampened by a repetitive clarion call to 'believe' all the science will be perfect first. Actually we hope so, but they don't know that much about the vaccine in real life, or prolonged duration, and certainly not about longer-term. I am in an age category that probably will be eligible for it almost right away, but unsure, until I learn more at least. Of course I'd prefer doing nothing but having at my side pills or monoclonal antibody nasal sprays, if it became necessary. That's even a longer-term proposition, but maybe not by much.
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