The Dow Jones Industrial Average (DJI) is in rally mode, reversing its premarket losses to jump 752 points after yesterday snapping its 10-day losing streak. The Nasdaq Composite Index (IXIC) and S&P 500 Index (SPX) are firmly higher as well, as investors unpack this morning's lukewarm PCE price index data.

Meanwhile, bond yields are sharply lower today, following last session's nearly seven-month highs for the 10- and 30-year notes. Investors are also eyeing Washington D.C. amid the potential for a partial government shutdown, which could begin tonight. 

Options traders are targeting plummeting Novo Nordisk A/S (NYSE: NVO) today, after the pharma name's weight-loss drug CagriSema showed disappointing results in its closely-watched phase 3 trial. So far, 57,000 calls and 31,000 puts have been exchanged, which is double the overall options volume typically seen at this point. The weekly 1/3 110-strike call is the most popular, followed by the weekly 12/27 90-strike call, with new positions being opened at the latter. At last look, NVO was down 20.6% at $82.12, and trading at 52-week lows. 

Mission Produce Inc (Nasdaq: AVO) is at the top of the Nasdaq today, after the company's upbeat fiscal fourth-quarter results. The shares were last seen up 22.6% to trade at $15.10, hitting roughly two-year highs. Since the start of the year, the equity is up 47.9%. 

United States Steel Corp (NYSE: X) is down 4.2% at $30.41, after the company announced a disappointing fourth-quarter forecast. The stock is on track for its eighth daily loss in the last nine sessions, though familiar support at the $30 level appears to be keeping losses in check. Year to date, X is down 37.4%. 

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