The major indexes are continuing their move higher this afternoon, as investors await tomorrow's release of November's consumer price index (CPI) data. The same day, the Fed will begin its two-day policy meeting. At last check, the Dow Jones Industrial Average (DJI) is up more than 240 points, while the S&P 500 Index (SPX) and Nasdaq Composite (IXIC) both carry modest gains. Despite today's positive price action, the Cboe Volatility Index (VIX) is gapping higher, last seen up 6.7% at 24.36. 

Options bulls are targeting DocuSign Inc (Nasdaq: DOCU) today. The stock was last seen up 5.2% at $51.71, jumping after the software company's better-than-expected third-quarter results, including billings and revenue. So far, 11,000 calls have exchanged hands, which is four times the intraday amount, compared to 3,732 puts. The most popular is the December 54 call, followed by the 51-strike call in the same series, with positions being opened at the former.

Harpoon Therapeutics Inc (Nasdaq: HARP) is one of the best-performing stocks on the Nasdaq today, last seen up 97% at $2.27 today. Last night, the drugmaker reported positive interim data for an early-stage study of its blood cancer treatment. HARP is trading at its highest level since July but is still down 67% in 2022.

Adicet Bio Inc (Nasdaq: ACET) is one of the worst stocks on the Nasdaq today, last seen down 40.1% at $10.35, following news that data from its Phase 1 clinical trial of its experimental CAR-T therapy in patients with relapsed or refractory B-cell non-Hodgkin's lymphoma is too early for a total response rate. The security hit a fresh annual low earlier today and suffers a 42.8% year-to-date deficit. 

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