Psychedelic Compound-Based Drug Stocks Portfolio -13% W/e Sept. 6th
Introduction
While the psychedelic compound-based drug market is expected to triple over the next few years which should create many winning stocks in the years to come, the stocks of the companies involved are having growing pains.
Some Background
Shares of clinical-stage companies developing treatments based on psychedelic compound-based drugs moved lower in early August after the U.S. Food and Drug Administration (FDA) rejected the use of MDMA (5-MeO-DMT or 5-MethOxy-N,N-DiMeThyltryptamine) for post-traumatic stress disorder (Source) as submitted by a private company, Lycos Therapeutics, based on concerns regarding Lykos’ therapy and its clinical trial designs. The FDA noted in their rejection notice, however, that they were still supportive of psychedelic development given that psychedelic drugs showed initial promise as potential treatments for mood, anxiety and substance use disorders.
Our Psychedelic Compound -Based Clinical-Stage Drug Stocks Portfolio
Below are the stock performances of the stocks of the4 largest psychedelic compound -based clinical-stage drug companies for the week-ending September 6th, in descending order, along with their area of focus, market capitalization and any pertinent news regarding their performances:
- Mind Medicine (MNMD): DOWN 1.7% w/e Sept. 6th
- Company Focus: lead product candidates include:
- Market Capitalization: $484M
- atai Life Sciences (ATAI): DOWN 8.5% w/e Sept. 6th
- Company Focus: Develops and invests in various therapeutics to treat depression, anxiety, addiction, and other mental health disorders and has announced:
- positive preliminary results from the Phase 1b trial of VLS-01, its proprietary oral trans-mucosal film formulation of mebufotenin that is applied to the buccal surface,
- plans to initiate a Phase 2 study for the treatment of treatment-resistant depression and
- plans to initiate a Phase 2 study (EMP-01) of an oral DMT for the treatment of social anxiety disorder by the end of FY’24
- Market Capitalization: $200M
- Company Focus: Develops and invests in various therapeutics to treat depression, anxiety, addiction, and other mental health disorders and has announced:
- Compass Pathways (CMPS): DOWN 11.4% w/e Sept. 6th
- Company Focus: CMPS is:
- in the process of developing COMP360, a psilocybin therapy that is in Phase III clinical trials for the treatment of treatment-resistant depression and
- in Phase II clinical trials for the treatment of post-traumatic stress disorder and anorexia nervosa.
- Market Capitalization: $453M
- Company Focus: CMPS is:
- GH Research (GHRS): DOWN 21.6% w/e Sept. 6th
- Company Focus: engages in developing various therapies (see pipeline here) to treat psychiatric and neurological disorders and focuses on the development of mebufotenin therapies, the new International non-proprietary name for DMT, for the treatment of patients with treatment-resistant depression (TRD).
- The company’s phase 2b trial for a mebufotenin inhalant has been very successful and is expected to end in the second half of this year
- and DMT is also being tested in a phase 2a trial for the treatment of postpartum depression (see details here).
- Market Capitalization: $428M
- News: GH Research Reports Second Quarter 2024 Financial Results
- Company Focus: engages in developing various therapies (see pipeline here) to treat psychiatric and neurological disorders and focuses on the development of mebufotenin therapies, the new International non-proprietary name for DMT, for the treatment of patients with treatment-resistant depression (TRD).
Summary
On average, the above 4 stocks were DOWN 13.1% w/e Sept. 6th (due primarily to GH Resources' 22% decline) following a 15.7% decline in August but they remain UP 12.1% YTD.
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Disclosure: None
This article has been composed with the exclusive application of the human intelligence (HI) of the author. No artificial intelligence (AI) technology has been deployed. ...
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