Our Psychedelic Compound-Based Clinical-Stage Drug Stocks Portfolio Was Down 16% In August

An Introduction

The psychedelic compound-based drug market is expected to triple over the next few years which should create many winning stocks in the years to come.

 

Some Background

Shares of clinical-stage companies developing treatments based on psychedelic compound-based drugs moved lower in early August after the U.S. Food and Drug Administration (FDA) rejected the use of MDMA (5-MeO-DMT or 5-MethOxy-N,N-DiMeThyltryptamine) for post-traumatic stress disorder (Source) as submitted by a private company, Lycos Therapeutics, based on concerns regarding Lykos’ therapy and its clinical trial designs. The FDA noted in their rejection notice, however, that they were still supportive of psychedelic development given that psychedelic drugs showed initial promise as potential treatments for mood, anxiety and substance use disorders.

 

Future Growth Expectations

Given that the psychedelic compound-based drug market is expected to triple over the next few years many winning stocks are likely to be created and to monitor their progress MunAiMarkets.com has created a Portfolio of the 4 largest such companies by market capitalization as follows:

 

The Psychedelic Compound-Based Clinical-Stage Drug Stocks Portfolio

Below are the stock performances of the 4 companies in the Portfolio in the month of August, in descending order, and YTD along with their area of focus, market capitalization and any pertinent news, analyses or commentary regarding their performances:

  1. Compass Pathways (CMPS): DOWN 5.8% in August; DOWN 17.8% YTD
  2. GH Research (GHRS): DOWN 7.4% in August; UP 97.9% YTD
    • Company Focus: engages in developing various therapies (see pipeline here) to treat psychiatric and neurological disorders and focuses on the development of mebufotenin therapies, the new International non-proprietary name for DMT, for the patients with treatment-resistant depression (TRD).
      • The company’s phase 2b trial for a mebufotenin inhalant has been very successful and is expected to end in the second half of this year
      • and DMT is also being tested in a phase 2a trial for the treatment of postpartum depression (see details here).
    • Market Capitalization: $546M
  3. atai Life Sciences (ATAI): DOWN 15.5% in August; DOWN 7.1% YTD
    • Company Focus: Develops and invests in various therapeutics to treat depression, anxiety, addiction, and other mental health disorders and has announced:
      • positive preliminary results from the Phase 1b trial of VLS-01, its proprietary oral trans-mucosal film formulation of mebufotenin that is applied to the buccal surface,
      • plans to initiate a Phase 2 study for the treatment of treatment-resistant depression and
      • plans to initiate a Phase 2 study (EMP-01) of an oral DMT for the treatment of social anxiety disorder by the end of FY’24
    • Market Capitalization: $218M
    • News/Analyses/Commentary:
  4. Mind Medicine (MNMD): DOWN 35.0% in August; DOWN 30.5% YTD
    • Company Focus: lead product candidates include:
      • MM-120, which is in phase 2 for the treatment of generalized anxiety disorder and attention deficit hyperactivity disorder, and
      • MM-402, a R-enantiomer of 3,4-methylenedioxymethamphetamine (MDMA), which is in phase I clinical trials for the treatment of core symptoms of autism spectrum disorder.
    • Market Capitalization: $493M
    • News/Analyses/Commentary:

Summary

On average, the above 4 stocks were DOWN 15.7% in August due to Mind Medicine’s 35% decline but they remain UP 32.5% YTD thanks to GH Resources 97.9% return over that time period.


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Disclosure: None

This article has been composed with the exclusive application of the human intelligence (HI) of the author. No artificial intelligence (AI) technology has been deployed. ...

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